Precision Oncology · Gulf Cooperation Council

Next-generation cancer medicines, built for Arab patients, born in the Gulf.

IO:TCR is developing TCR bispecific immunotherapies — the most advanced class of precision cancer medicine — to serve patients across the Gulf and around the world. Our founders bring direct experience in the research, development, and commercialisation of TCR-based therapies.

  • FDA & EMA approved class
  • >90% tumour proteome reach
  • Gulf-rooted R&D
+143%
Projected rise in GCC cancer cases by 2040
USD 112B
Global cancer immunotherapy market by 2032
>90%
Of tumour proteins addressable with TCR bispecifics

Vision & Mission

A globally influential oncology biotech, born in the Gulf.

IO:TCR is a next-generation, precision oncology biotechnology company rooted in the Gulf Cooperation Council region. We aim to revolutionise global cancer treatment and address healthcare inequality by developing TCR bispecific immunotherapies — medicines with high specificity, low toxicity, and a proven path through global regulators.

We prioritise Arab cancer patients while accessing global markets, targeting high-prevalence cancers including lung, breast, and colorectal — and ensuring Arab patient needs and Arab cancer genetics are at the forefront of every programme we run.

Beyond medicines for Arab populations, we are building home-grown Gulf R&D capability — developing regional scientific expertise, infrastructure, and intellectual property designed to deliver both regional impact and global out-licensing reach.

Precision

Targeting cancer with the specificity of T cell receptors — not just cell-surface proteins.

Population-relevant

Designed with Arab HLA genetics in mind, while serving patients globally.

Proven class

Our Founders bring direct experience in the R&D and commercialisation of TCR therapies.

A clinician examines an Arab patient using ultrasound, illustrating IO:TCR's focus on Arab patient care.
Built for the patients we serve — and the genetics they carry.

Our Platform

TCR Bispecifics — the next frontier of immunotherapy.

T cell Receptor (TCR) Bispecifics are a next-generation class of cancer immunotherapy. They guide the body’s own T cells to recognise and destroy cancer cells — including those that evade traditional therapies — by accessing previously inaccessible targets inside the cell.

Diagram showing a cancer cell on top, a TCR bispecific molecule in the middle, and an immune cell at the bottom — illustrating how TCR bispecifics bridge T cells to tumours.
  • >90% tumour proteome reach

    Antibody drugs see <10% of cancer targets. TCR bispecifics unlock the rest — the intracellular world.

  • “Off-the-shelf” medicines

    No personalised cell manufacture. Predictable supply, predictable cost.

  • Manageable safety profile

    Engineered for high specificity and low toxicity — designed for global regulatory acceptance.

  • Clinically proven class

    KIMMTRAK, the world’s first approved TCR bispecific, doubled survival in metastatic uveal melanoma.

The Opportunity

A rising tide of need — and a rare window of advantage.

47%

Projected increase in new global cancer cases by 2040.

+460%

Rise in cancer incidence among the over-70s in the GCC by 2040.

USD 450K

Per patient, per course of precision immunotherapy treatment.*

CAGR 16.5%

Cancer immunotherapy is one of the fastest-growing segments in healthcare.

*Reference: 6‑month course of KIMMTRAK (tebentafusp) in the USA.

A Gulf Arab scientist and a female colleague in a lab coat review data together on a tablet in a modern laboratory.

Aligned with Gulf national visions

A strategic asset for the Gulf’s life-sciences ambitions.

IO:TCR is more than a pharmaceutical investment — we are a regional strategic asset aligned with the national visions of GCC member states. By building R&D, manufacturing, and clinical capability in the Gulf, we support national biotechnology strategies and help position the region as a global biotech hub.

Saudi Arabia

Vision 2030 · National Biotechnology Strategy

Biomanufacturing, genomics and vaccine localisation — with the ambition of becoming the leading biotech hub in MENA by 2030.

United Arab Emirates

We the UAE 2031 · Emirates Drug Establishment

Abu Dhabi’s HELM life-sciences cluster and the Emirati Genome Programme, alongside Dubai Science Park’s life-sciences community.

  • High-value contribution to non-oil economic diversification
  • Increased life expectancy and improved public health
  • International knowledge transfer and localised scientific excellence
  • Skilled employment for Gulf research and biotech graduates
  • IP ownership anchored in the region

For Investors

Well positioned for early-stage growth.

We are advancing multiple precision cancer assets, building a Gulf biotech ecosystem, and generating IP designed for global out-licensing. Investor and partnership enquiries are welcome from qualified institutions, family offices, and sovereign capital.

Request more information

Get in Touch

We welcome your interest.

IO:TCR is currently operating in stealth. For partnership, investment, scientific collaboration, or media enquiries, please reach our central contact team.